software felix 95.0 (Biosym Technologies)
90
Structured Review
Biosym Technologies
software felix 95.0
Software Felix 95.0, supplied by Biosym Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/felix+95%2E0+software/felix+software+package/pmc00419607-100-16-19
Average 90 stars, based on 1 article reviews
Software Felix 95.0, supplied by Biosym Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/felix+95%2E0+software/felix+software+package/pmc00419607-100-16-19
Average 90 stars, based on 1 article reviews
software felix 95.0 - by Bioz Stars,
2026-09
90/100 stars
Images
Related Articles
Nuclear Magnetic Resonance:Article Title: Quantitative Analysis of Peptides with NMR Spectroscopy Article Snippet: The determination of peptide concentration with 1H nuclear magnetic resonance (NMR) spectroscopy using an internal standard or an external standard in a sealed glass capillary was investigated for three tyrosine-containing tripeptides.. Trimethylsilylpropionic acid (TSP) and maleic acid were tested as external standards for quantitation by proton NMR.. Although comparable results were obtained for either standard, the performance of maleic acid was found to be superior because of its better long-term stability in the sealed capillary. Article Title: Modified pulsed-field gradient NMR experiments for improved selectivity in the measurement of diffusion coefficients in complex mixtures: application to the analysis of the Suwannee River fulvic acid. Article Snippet: To simplify the complex 1H NMR spectrum of a fulvic acid sample and gain structural and molecular size information, spectral editing techniques were used in conjunction with a general PFG NMR pulse sequence.. These editing techniques exploit differences in T1 and T2 relaxation times as well as differences in coupling constants.. The experiments were initially performed on a model mixture of glutamic acid and ethyl acetate in order to validate the method as a technique for measurement of diffusion coefficients. Article Title: Origin of the correlation time dependence of coherence transfer distortions in rotating frame cross-relaxation spectra. Article Snippet: HOHAHA distortions in conventional (CW) ROESY experidition of maximum HOHAHA transfer.. Thus, choosing a ments are known to be prominent when the frequency of the spintransmitter position where there are no crosspeaks perpenlock field is near the midpoint between the resonance frequencies dicular to the diagonal minimizes HOHAHA distortions in of a pair of coupled spins.. That the disappearance of these distorconventional ROESY spectra. Article Title: Picosecond to hour time scale dynamics of a "three finger" toxin: correlation with its toxic and antigenic properties. Article Snippet: Toxin R from Naja nigricollis (61 amino acids, four disulfide bridges) belongs to the “three finger” fold family, which contains snake toxins with various biological activities and nontoxic proteins from different origins.. In this paper, we report an extensive 1H and 15N NMR study of the dynamics of toxin R in solution.. 15N relaxation, 1H off-resonance ROESY, and H-D exchange experiments allowed us to probe picosecond to hour motions in the protein. Article Title: Immobilization of the C-terminal extension of bovine alphaA-crystallin reduces chaperone-like activity. Article Snippet: Spectra were processed with either Varian or Bruker software or, in the main, with Article Title: Is the structure of the N-domain of phosphoglycerate kinase affected by isolation from the intact molecule? Article Snippet: The structural integrity of the isolated N-domain (residues 1-174) of Bacillus stearothermophilus 3-phosphoglycerate kinase (PGK) has been investigated using heteronuclear NMR spectroscopy.. Analysis of 13C chemical shifts, amide protection, and comparison of observed and expected sequential NOE intensities calculated from the crystal structure of the domain in the intact protein indicate that the secondary structure of the isolated domain is unchanged from that found in the intact molecule.. Markedly shifted 1H resonances, amide protection, and long-range NOEs indicate that the tertiary structure is similarly unaffected. Article Title: Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy. Article Snippet: The ferritin IRE, a highly conserved (96-99% in vertebrates) mRNA translation regulatory element in animal mRNA, was studied by molecular modeling (using MC-SYM and DOCKING) and by NMR spectroscopy.. Cobalt(III) hexammine was used to model hydrated Mg2+.. IRE isoforms in other mRNAs regulate mRNA translation or stability; all IREs bind IRPs (iron regulatory proteins). Article Title: Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale. Article Snippet: Using a combination of nuclear magnetic resonance (NMR) spectroscopy experiments and molecular dynamics, we have analyzed the structure and dynamics of a complex between the bisnaphthalimide drug LU-79553 and the DNA duplex d(ATGCAT)2.. LU-79553 is a DNA-binding topoisomerase II inhibitor that is particularly effective against human solid tumors that are refractory to other drugs.. We have found that the two naphthalimide chromophores of the drug bisintercalate at the TpG and CpA steps of the DNA hexanucleotide, stacking mainly with the purine G and A bases from opposite strands. Software:Article Title: Quantitative Analysis of Peptides with NMR Spectroscopy Article Snippet: The determination of peptide concentration with 1H nuclear magnetic resonance (NMR) spectroscopy using an internal standard or an external standard in a sealed glass capillary was investigated for three tyrosine-containing tripeptides.. Trimethylsilylpropionic acid (TSP) and maleic acid were tested as external standards for quantitation by proton NMR.. Although comparable results were obtained for either standard, the performance of maleic acid was found to be superior because of its better long-term stability in the sealed capillary. Article Title: Modified pulsed-field gradient NMR experiments for improved selectivity in the measurement of diffusion coefficients in complex mixtures: application to the analysis of the Suwannee River fulvic acid. Article Snippet: To simplify the complex 1H NMR spectrum of a fulvic acid sample and gain structural and molecular size information, spectral editing techniques were used in conjunction with a general PFG NMR pulse sequence.. These editing techniques exploit differences in T1 and T2 relaxation times as well as differences in coupling constants.. The experiments were initially performed on a model mixture of glutamic acid and ethyl acetate in order to validate the method as a technique for measurement of diffusion coefficients. Article Title: Origin of the correlation time dependence of coherence transfer distortions in rotating frame cross-relaxation spectra. Article Snippet: HOHAHA distortions in conventional (CW) ROESY experidition of maximum HOHAHA transfer.. Thus, choosing a ments are known to be prominent when the frequency of the spintransmitter position where there are no crosspeaks perpenlock field is near the midpoint between the resonance frequencies dicular to the diagonal minimizes HOHAHA distortions in of a pair of coupled spins.. That the disappearance of these distorconventional ROESY spectra. Article Title: Picosecond to hour time scale dynamics of a "three finger" toxin: correlation with its toxic and antigenic properties. Article Snippet: Toxin R from Naja nigricollis (61 amino acids, four disulfide bridges) belongs to the “three finger” fold family, which contains snake toxins with various biological activities and nontoxic proteins from different origins.. In this paper, we report an extensive 1H and 15N NMR study of the dynamics of toxin R in solution.. 15N relaxation, 1H off-resonance ROESY, and H-D exchange experiments allowed us to probe picosecond to hour motions in the protein. Article Title: Immobilization of the C-terminal extension of bovine alphaA-crystallin reduces chaperone-like activity. Article Snippet: Spectra were processed with either Varian or Bruker software or, in the main, with Article Title: Is the structure of the N-domain of phosphoglycerate kinase affected by isolation from the intact molecule? Article Snippet: The structural integrity of the isolated N-domain (residues 1-174) of Bacillus stearothermophilus 3-phosphoglycerate kinase (PGK) has been investigated using heteronuclear NMR spectroscopy.. Analysis of 13C chemical shifts, amide protection, and comparison of observed and expected sequential NOE intensities calculated from the crystal structure of the domain in the intact protein indicate that the secondary structure of the isolated domain is unchanged from that found in the intact molecule.. Markedly shifted 1H resonances, amide protection, and long-range NOEs indicate that the tertiary structure is similarly unaffected. Article Title: Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy. Article Snippet: The ferritin IRE, a highly conserved (96-99% in vertebrates) mRNA translation regulatory element in animal mRNA, was studied by molecular modeling (using MC-SYM and DOCKING) and by NMR spectroscopy.. Cobalt(III) hexammine was used to model hydrated Mg2+.. IRE isoforms in other mRNAs regulate mRNA translation or stability; all IREs bind IRPs (iron regulatory proteins). Article Title: Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale. Article Snippet: Using a combination of nuclear magnetic resonance (NMR) spectroscopy experiments and molecular dynamics, we have analyzed the structure and dynamics of a complex between the bisnaphthalimide drug LU-79553 and the DNA duplex d(ATGCAT)2.. LU-79553 is a DNA-binding topoisomerase II inhibitor that is particularly effective against human solid tumors that are refractory to other drugs.. We have found that the two naphthalimide chromophores of the drug bisintercalate at the TpG and CpA steps of the DNA hexanucleotide, stacking mainly with the purine G and A bases from opposite strands. |